Healthy isn?t something you are or aren?t. It?s a hundred little things: eating a banana, walking in the park, putting a bandage on a boo-boo, playing tag, reading up on ways to keep you and your family well and safe. It?s a balance between living well and taking care, and you can start right where you are.
A blog by Christina Elston
Healthy isn't something you are or aren't. It's a hundred little things: eating a banana, walking in the park, putting a bandage on a boo-boo, playing tag, reading up on ways to keep you and your family well and safe. It's a balance between living well and taking care, and you can start right where you are.


Posts Tagged ‘pregnancy’

Untreated Fever During Pregnancy More Than Doubles Autism Risk

Thursday, May 24th, 2012

Researchers from the UC Davis MIND Institute have linked untreated fever during a mother’s pregnancy with increased risk of autism or developmental delays in her child. In a large study including detailed information on participants, they found that women who reported fever had 2.12 times higher odds of having a child with autism and 2.5 times higher odds of having a child with developmental delay than women who reported no fever during pregnancy, or those who took anti-fever medication.

The study involved more than 1,100 women and their babies.

“If someone has fever during pregnancy they should take it seriously,” says lead study author Ousseny Zerbo, now a postdoctoral researcher with Kaiser Permanente, adding that this means taking over-the-counter anti-fever medication, and seeking medical attention if the fever persists. “Particularly during pregnancy, a lot of people don’t want to take any medication,” Zerbo says.

But treating fever also treats the acute inflammation that accompanies it, and this could be the connection between fever and autism risk. Another recent study based on the same data found that mothers who were obese or had diabetes – conditions associated with chronic inflammation in the body – were also more likely to have children with autism.

Both studies were based on data from the Childhood Autism Risk from Genetics and the Environment (CHARGE) study, which collected information on a large group of California children ages 2 to 5.

Infection with bacteria or viruses triggers a healing response that releases inflammatory elements from white blood cells into the bloodstream. Called cytokines, these elements are able to cross the placenta, and could impact a developing baby’s brain. “I think we need to do a lot more study regarding inflammation during pregnancy,” says Zerbo.

The study was published online May 23 in the Journal of Autism and Developmental Disorders.

 

Babies Born By C-Section Twice As Likely To Be Obese

Wednesday, May 23rd, 2012

Rates of both Cesarean section birth and child obesity have soared in recent decades, and it turns out that the way children are brought into the world could have a big impact on their weight. Kids born by c-section have a different composition of bacteria in their guts than children born vaginally do, and scientists theorize this might make c-section babies more likely to be obese.

The weight difference between c-section and vaginally delivered babies showed up when researchers from Children’s Hospital Boston looked at 1,255 deliveries in eastern Massachusetts between 1999 and 2002. They measured and weighed the babies at birth, at 6 months, and at age 3.

One in four of the babies were delivered by c-section (a rate lower than the national average of one in three). Moms in the study who delivered by c-section tended to weigh more than those delivering vaginally, so the birthweight of their babies tended to be higher. They also breastfed their babies for a shorter period of time.

Even when these and other factors were taken into account, babies delivered by c-section were twice as likely to be obese by age 3 as those delivered vaginally. Just under 16% of the children delivered by c-section were obese, compared with only 7.5% of those born vaginally. Nationally, the obesity rate among kids ages 6-11 is nearly 20%, according to government figures.

Previous research has shown that children born by c-section have higher numbers of Firmicutes bacteria and lower numbers of Bacteroides bacteria in their guts than those born vaginally. This could increase the energy their bodies extract from food, and stimulate cells to boost insulin resistance, inflammation and fat deposits, say the study authors. They point out that the apparent link between cesarean delivery and obesity should prompt mothers to avoid c-sections unless they are medically necessary.

The research appears online in the Archives of Disease in Childhood, a BMJ publication.

Obesity in Pregnancy Linked to Autism in Kids

Monday, April 9th, 2012

Moms who struggle with diabetes, hypertension or obesity while pregnant are more likely to have children with autism spectrum disorders (ASD) or developmental delays, a new study has revealed.

The findings come on the heels of a well-publicized report by the national Centers for Disease Control, which revealed that autism and ASD diagnoses continue to rise, with one in 88 children in the United States now affected.

In this new study, researchers from the MIND Institute at UC Davis and the Vanderbilt University School of Medicine looked at California children, ages 2 to 5, enrolled in a population-based study from 2003 to 2010. Of the group, 500 had ASD, 200 had developmental delays and 300 were developing typically. The researchers reviewed medical records for the children’s mothers during pregnancy, asked the mothers about a history or diagnosis of diabetes or hypertension, and noted the women’s body-mass indexes (BMIs), a measure of weight related to height.

Women who were obese before pregnancy had a 60 percent higher chance of having a child with ASD, and twice the risk of having a child with a developmental delay. Those with high blood pressure or diabetes before or during pregnancy were also more likely to have children with ASD or delays, but the increase wasn’t statistically significant.

Diabetes during pregnancy has previously been associated with developmental problems in children, but not consistently linked with ASD.

Obesity is a significant risk factor for hypertension and diabetes, and all three conditions impact the body’s ability to regulate blood sugar (glucose). Exposing a developing fetus to too much glucose can trigger a condition called fetal hypoxia (increased metabolism leading to lack of oxygen), as well as iron deficiency – both of which can profoundly impact development of the brain.

The authors point out that nearly 60 percent of U.S. women of childbearing age are overweight, one-third are obese, and 16 percent are at risk of diabetes.  “Our findings raise concerns that these maternal conditions may be associated with neurodevelopmental problems in children and therefore could have serious public health implications,” they note.

The study appears in the April 9 issue of the medical journal Pediatrics.

Pharmacies Handing Teens Misinformation, Not Plan B Contraception

Tuesday, March 27th, 2012

A new study finds that pharmacies often gave 17-year-olds wrong information about – and denied them access to – the emergency contraceptive sold under the brand name Plan B One Step. Meanwhile, doctors calling the same pharmacies got accurate facts.

Researchers from Boston Medical Center/Boston University School of Medicine orchestrated calls to 943 pharmacies, covering every pharmacy in Nashville, Tennessee; Philadelphia, Pennsylvania; Cleveland, Ohio; Austin, Texas and Portland, Oregon. Female callers posed first as 17-year-old girls, then two weeks later as physicians seeking advice for their 17-year-old patients.

Around 80 percent of the pharmacies reported having the drug, available over the counter to women ages 17 and older and by prescription to younger teens, in stock. But when callers posing as 17-year-olds asked if they could get the medication, 19 percent were told that they could not get it under any circumstances. Only 3 percent of callers posing as physicians were told their 17-year-old patients could not get the drug.

Almost 640,000 unplanned pregnancies occur in girls ages 15-19 in the U.S. each year.

The study didn’t look into reasons behind the misinformation, but the authors noted that “teen” callers spoke to people who identified themselves as pharmacists less often than “doctors” (3 percent vs. 12 percent of the time) and that other pharmacy employees might not be as well informed about rules for dispensing the medication, or might not want teens to have access.

“Given the history of emergency contraception, the politics around it and also the frequent changes to the dispensing regulations, there are lots of sources of misinformation,” says lead author Tracey Wilkinson, M.D., a general pediatrics fellow at the university.

Wilkinson says she doesn’t know of any national standard that determines who answers questions about medication at pharmacies. A representative from CVS Caremark, which claims to be the largest pharmacy health care provider in the U.S., says that a question about whether emergency contraception was in stock and at what age a person can purchase it without a prescription would not require a pharmacist to answer.

Wilkinson advocates improved education for pharmacy staff and adolescents, and says doctors could consider issuing prescriptions for teen patients even when they aren’t required by law, to help guarantee timely access.

Meanwhile, she is studying the possibility of providing the medication in advance to sexually active teenagers. “That way, they already have emergency contraception if they need it,” she says. “Because teenagers are at such risk for unplanned pregnancy, it is imperative that we figure out ways to guarantee them this safe and effective form of contraception.”

Her study appears in the March 26 issue of Pediatrics.

For Healthy Babies, Eat Your Cereal

Tuesday, January 10th, 2012

It’s as easy as eating a bowl of cereal, and if all women of childbearing age did it, hundreds of California babies would be born healthy – rather than with defects of the brain and spinal cord that can cause serious disability or death.

That’s the message from the California Dept. of Public Health this week as they focus on getting women to add enough folic acid to their diets to prevent these birth defects, called neural tube defects (NTDs). Folic acid is a B vitamin needed by every cell in the body for growth and repair. When women have at least 400 micrograms of folic acid in their daily diet (about the amount in a bowl of fortified cereal) they reduce their risk of having a child born with NTDs by 50 to 70 percent.

Waiting until you’re pregnant, or planning to become pregnant, isn’t an option. Around 45% of births in California are unplanned, and NTDs develop during the early months of pregnancy, often before a woman knows she’s going to have a baby. The only way to be sure there’s enough folic acid in your diet at the right time is to start now.

NTDs are the most common birth defect in California, impacting one in 1,480 pregnancies, and about 400 babies a year. And less than 50 percent of non-pregnant women reported consuming folic acid regularly in a statewide survey.

For more information about preconception health, visit the Every Woman California website, www.everywomancalifornia.org.

Be Cautious With Cold Meds During Pregnancy

Monday, December 19th, 2011

Colds and flu can be especially miserable for women with a baby on the way. For many, it’s natural to grab an over-the-counter remedy for relief, but experts from a national pregnancy health information line advise slowing down.

The CTIS (California Teratogen Information Service) Pregnancy Health Information Line gets lots of calls this time of year from women with questions about medications for upper respiratory symptoms. (Teratology is the study of birth defects caused by exposure to different substances during pregnancy.) Here are some top tips from experts at the nonprofit, housed at UC San Diego:

• Less is more. Take medications that have only ingredients designed to treat your specific symptoms. Avoid combination medications that combine things like cough suppressants and antihistamines, so you don’t end up taking something you don’t need.

• Easy on the decongestant. Most studies show that oral decongestants are probably safe during the first trimester, but there is a very low risk of vascular issues in the fetus so it’s best to skip them if you can. Instead, try saline drops or a short-term decongestant nasal spray.

• Keep a lookout for herbs. Many over-the-counter medications now also contain herbal ingredients, but these haven’t necessarily been tested for safety in pregnancy. Choose medicines with the fewest ingredients possible.

• Keep lozenges in check. While most throat lozenges contain mainly sugar, some also have doses of vitamin C and zinc. The recommended daily dose of vitamin C during pregnancy is 80-100 mg, and zinc is limited to just 11 mg per day. Read lozenge labels so you don’t overdo it.

• Choose alcohol-free cough syrup. Some cough syrups contain up to 10 percent alcohol, which isn’t good for your baby. Choose only medications that say they are alcohol-free.

If you’re unsure about a particular medication, consult your OB-GYN for help. In California, you can also contact the CTIS Pregnancy Health information line at 800-532-3749. And anyone can visit them at CTISPregnancy.org, where experts answer questions via live online chat or email, and you’ll find fact sheets, a blog and a community forum.

Cord Blood Gives Woman a New Birthday

Friday, May 13th, 2011

Wendy Gorrell, here with her husband, is doing well after a cord blood transplant gave her a new immune system.

Wendy Gorrell, here with her husband, is doing well after a cord blood transplant gave her a new immune system.

Wendy Gorrell laughs as she explains how the immune systems of a little Italian boy and a little American girl battled it out to determine which one would save her life. She has never met either child, and never will, but she now knows the outcome: “I now have the same blood stem cells as an American little girl who’s out there,” Gorrell says.

The stem cells of both children were collected from their umbilical cords the day they were born, and their mothers donated the cord blood to the registries here and abroad, where they waited for someone who needed a donor.

In 2007 Gorrell, who has no children of her own and lives with her husband in Ventura, was diagnosed with lymphoblastic lymphoma, an immune system cancer similar to leukemia that starts in the lymph system. She underwent eight rounds of “intense” chemotherapy at UCLA, staying in the hospital each time. “My immune system dropped so low that I couldn’t risk being out in public,” she explains. But her body responded well.

Then, in 2009, doctors discovered that the treatment had damaged Gorrell’s bone marrow, leading to MDS/AML, a form of leukemia. She now needed a bone marrow transplant, so her doctors searched for an adult donor, the ideal because doctors can harvest a greater number of stem cells from an adult. No match was found. Read on …

Low Levels of Lead Raise Pregnant Women’s BP

Wednesday, February 9th, 2011

pregnantBlood lead levels well below government safety standards – levels the CDC suggests could be found in 10%-25% of U.S. women of childbearing age – can raise a woman’s blood pressure during pregnancy, a study in this month’s edition of Environmental Health Perspectives suggests.

The study of 285 pregnant women was too small to determine whether lead could also increase risk for preeclampsia (a life-threatening spike in blood pressure during pregnancy), says Lynn Goldman, M.D., dean of the school of public health at George Washington University and lead author of the study. “Much larger studies” are needed to fully assess this and other possible health impacts, she says. Any increase in the blood pressure of pregnant women, however, is of concern.

The CDC safety threshold for lead in the blood of small children and pregnant women is 5 micrograms (ug) per deciliter (dL). Among the women studied, about 25% had blood lead levels of 1 ug/dL or higher, but that was enough to raise their blood pressure. And at 2 ug/dL, the blood pressure increase was enough to “significantly increase the percentage of women at risk for adverse health effects,” Goldman says. Researchers didn’t record how the women were exposed to lead, but according to Goldman levels this low wouldn’t likely come through occupational exposure.

Exposures before a woman is even pregnant could also be a problem, because lead is stored in the bones for many years – long enough, Goldman says, for exposure as a young girl to pose a problem during pregnancy. Blood lead levels in the U.S. have steadily declined over the past two decades thanks to bans on lead in gasoline and drinking water regulations. If the results of this study are confirmed with further research, it suggests that efforts to reduce everyone’s exposure to lead should continue.

Funding sources for the research included the EPA, the National Institute of Environmental Health Sciences, the CDC, and Johns Hopkins.

Antibacterial Ingredient May Not Be Safe For Pregnancy

Monday, November 29th, 2010

triclosanWhen you’re going to have a baby, you want to take the best care of yourself and your home. But a common chemical thought to help keep dangerous bacteria at bay could be a danger in itself, according to a new study from the University of Florida.

The antibacterial agent triclosan is found in everything from soaps (for both people and household cleaning) to sponges, lotions to socks. But researchers have now found that it also keeps estrogen from getting to the developing fetus. Triclosan hinders an enzyme called estrogen sulfotransferase, which helps move estrogen through the placenta.

The estrogen that reaches the fetus plays a crucial role in brain development and the regulation of genes. Estrogen also impacts how much oxygen the baby gets from the mother.

Authors of the study, reported in November in Environment International, say that they don’t know how much triclosan would need to be present in a woman’s body before it caused a problem. Because the chemical isn’t naturally broken down in the environment, everyone has low levels in their bodies. Previous studies have linked triclosan to problems with hormone regulation and other health effects, and the FDA decided in April to study the chemical more closely. Their findings are due this coming spring.

Meanwhile, authors of the Florida study recommend that pregnant women avoid antibacterial soaps and other products containing triclosan. If it’s part of the product, it will be listed on the label.

Putting Your Best (Pregnant) Foot Forward

Wednesday, May 26th, 2010

pregnant-shoeSo much of your body changes during pregnancy, and your feet are no exception. Relaxin, the hormone that allows your pelvis to open to carry and deliver your baby, makes the ligaments in the feet more flexible so that your foot becomes both wider and longer. They can grow up to half a shoe size.

To make your path to motherhood a little smoother, the American College of Foot and Ankle Surgeons recommends a few fixes for common foot problems:

feetPainful, swollen feet – Fluid buildup in the feet from the weight and position of the baby can cause swelling and pain. To reduce this, put your feet up whenever you can, stretch your legs often and wear wide, comfortable shoes. Try not to cross your legs when sitting.

feetPainful arches – This can come from stress on the ligament that holds up the arch of your foot. Stretch every morning (holding onto your toes and gently pulling your foot as far flexed as it will go), don’t go barefoot, and wear supportive shoes with low heels.

feetFoot cramps – Increased hormone levels during pregnancy can cause these. The best way to prevent them is to keep circulation moving by rotating your ankles and elevating your feet when seated. Walking and daily stretching of your calves can also help.

feetIngrown toenails – If you’re outgrowing your shoes, the tight fit can cause ingrown toenails. Wider shoes are your best bet. If you do get an ingrown nail, let a professional handle it. DIY “surgery” could lead to a nasty infection.

For more information about all things foot related, visit www.FootHealthFacts.org.